Leptin Resistance and Obesity

leptin resistance

What To Do When Your Body Refuses to Lose Weight!

When Leptin has lost its ability to function well in the body – this is called Leptin Resistance.  A Leptin resistant person needs more and more Leptin to tell the brain it is satisfied and that you don’t need more food. You become leptin-resistant by the same way/mechanism that you become insulin-resistant – this happens due to continuous overexposure to high levels of the leptin hormone. Eating a diet that is particularly high in sugar (like fructose), grains, and processed foods – it is the same diet that will also increase inflammation in your body – the sugar gets metabolized in your fat cells.  The metabolized fat releases surges in leptin.  Over time, if your body gets exposed to too much leptin, then it becomes leptin resistant, just as your body can become resistant to insulin. The only way to re-establish proper leptin (and insulin) signaling is to prevent those surges, and the only known way to do that is taking a proper diet. The bottom line is diet can have a more profound effect on your health compared to the known modalities of medical treatment around the globe.

A strategic whole food diet, as detailed in an  our free diet free nutrition plan, that emphasizes good fats and avoids blood sugar spikes coupled with targeted supplements will enhance insulin and leptin sensitivity so that your brain can once again hear the feedback signals from these hormones

The Downward Spiral

As I had said earlier, Leptin is the satiety hormone produced by fat cells. It would seem logical that those with more fat cells would produce more Leptin, which would in turn signal the body to eat less food. This is the process that would lead to weight normalization. This over-simplified idea is great in theory, but doesn’t always occur, especially in those with damaged metabolisms or endocrine problems (which includes most overweight people).

According Kent Holtorf article-Long Term Weight Loss:

“The problem is not in the production of leptin, but rather, studies show that the majority of overweight individuals who are having difficulty losing weight have a leptin resistance, where the leptin is unable to produce its normal effects to stimulate weight loss. This leptin resistance is sensed as starvation, so multiple mechanisms are activated to increase fat stores, rather than burn excess fat stores. Leptin resistance also stimulates the formation of reverse T3, which blocks the effects of thyroid hormone on metabolism.”

Thyroid is the one that control the endocrine hormones which may affect your body’s metabolism. Here is the puzzle. The person is eating excess food, the body thinks it is starving, and therefore tells the person to eat more. It’s easy to see how this cycle could contribute to weight gain!

Causes of Leptin resistance

There several known factors that contribute to contribute to leptin resistance

As with all hormone issues, Leptin resistance is a complex issue with no singular cause, but there are many factors that can negatively impact on Leptin levels including:

  • Consumption of food that has fructose  (especially in forms like High Fructose Corn Syrup)
  • High stress levels
  • Eating of a lot of simple carbohydrates
  • Lack of  inadequate sleep
  • High insulin level in the body-(you know both leptin and insulin work in tandem with each other)
  • Eating more than what you need.
  • Exercising excessively,  especially if your hormones are already damaged
  • Grain and leptin consumption

  Chances that you have Leptin Resistance issues

There are several pointers regarding your leptin status that tells you that you may be having leptin issues that would need to be addressed. It could be that you are having a problem/ troubles sticking to a certain diet May be you have been on a certain diet that you found very hard to stick to. Do not worry, you are not the problem. It is the excess leptin in your body.

Do you crave for foods? Are you the kind of a lady that hardly an hour passes without visiting the fast food joints you are used to patronizing? Are you overweight?  May be your weight has been the greatest hindrance to your happiness and rips you off of your self-esteem. Do not blame yourself or curse those ‘unforgiving genes’. It is your high leptin level.

Sometimes you may feel that persistent urge to snack. This happens more especially at night, few hours after dinner. These are all indications that you could have some leptin issues.

Drug treatments are not likely to solve leptin resistance, just as they are ineffective and even counterproductive for insulin resistance. The ideal way to correct leptin resistance is through your diet. A strategic whole food diet that emphasizes good fats and avoids blood sugar spikes will enhance insulin and leptin sensitivity.

Obesity can trigger cancer growth Leptin and cancer

Cancer related deaths. The growing population of cancer patients’ is alarming. These are the news that has been hitting our screens. It is something devastating to think about, given the grim statistics of ever increasing number of patients.  Leptin and insulin resistance is front and center of the issue of obesity. Obesity is now a problem of epic proportions as it increases your risk to a wide variety of other diseases. In fact, there are at least 20 different diseases and conditions that are directly attributable to being overweight. This societal problem has emerged in just the past four decades, largely due to misguided dietary guidelines.

Cancer is one disease related to excess weight. According to recent research, being obese promotes the growth of existing tumors regardless of diet, which may help explain why lean cancer patients often have better outcomes than their obese counterparts.

The animal study, published in the Oct. 15 issue of the journal Cancer Research showed that tumors in obese mice grew much faster than in lean mice eating the same diet. According to the authors:

“In this study, we show that obesity facilitates tumor growth in mice irrespective of concurrent diet, suggesting a direct effect of excess white adipose tissue [fat tissue]. When transplanted into mice, adipose stromal cells can serve as perivascular adipocyte progenitors that promote tumor growth, perhaps helping explain the obesity-cancer link.”

Obesity is known lead to lifestyle diseases and to a woman, it means more than this, especially during these times when appearance means everything. Obesity can make you sexually unattractive! Do you have this problem? Do you want to achieve amazing weight loss without any pain? What do you need to do?  I will be discussing this later in this book.

Fight Obesity and Reduce Tumor Potential

Obesity can trigger the development of tumors in your body. As stated in the featured journal, the implications are clear:

“Reduce obesity before the appearance of tumors and after. Previous research has shown exercise can convert cancer-boosting “white” fat cells to the more health-promoting “brown” fat (a heat-generating type of fat that burns energy instead of storing fat)”.

If you won’t hinge your health and well-being on that, you're likely going to miss the boat and join the ranks of cancer statistics. Research has shown that certain groups of people tend to have more brown fat than others, and there are direct correlations between the activation of brown fat and metabolic measures of good health. For example slim people have more brown fat than obese people do and younger people have more brown fat than elderly people. Besides people having a normal blood sugar levels have more brown fat than those with high blood sugar.

So one may ask whether there is a way of converting harmful white fat into health promoting brown fat and without using drugs (supplements) the answer is, a good yes, there is. In one mouse study, (never dismiss them as animal studies) the animals converted white fat into brown fat simply by exercising. The study, published in the journal Disease Models and Mechanisms in May 2012 found that, during exercise, the animals' muscles released an enzyme called iris in, which sparked the conversion white fat cells to brown fat. Another study published in Nature also suggests irisin may be a key to explaining the therapeutic benefits of exercise on metabolic disease. The authors wrote:

“Irisin acts on white adipose cells in culture and in vivo to stimulate UCP1expression and a broad program of brown-fat-like development. Irisin is induced with exercise in mice and humans, and mildly increased irisin levels in the blood cause an increase in energy expenditure in mice with no changes in movement or food intake. This results in improvements in obesity and glucose homeostasis.”

In other words, the study emphasized a good exercise as a key to conversion of white fat-the unhealthy fat- to brown fat. By exercising, you reduce the risk of developing cancer.

So in a summary form, exercise to avoid being obese, which increases your chances of developing cancer.

Leptin Resistance and Obesity this ebook will cover everything you will need to know about how Leptin, Insulin and other hormones are linked to Obesity Diabetes and more. Check it out on Smashwords.com

Leptin Resistance, Insulin Resistant Diabetes and Long Life

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